LDN is most commonly being used for Chronic Fatigue, Multiple Sclerosis, Autoimmune disorders, Chronic Pain, autoimmune thyroid diseases and various cancers. These disorders and diseases seem to respond very well to LDN.
This is a wide range of diseases and many people find it difficult to understand how one drug can have a positive effect on all these problems. It does this by:
Increase endorphin release
Increase endorphins modulate the immune response
This reduces the speed of unwanted cells growing Naltrexone is an antagonist for at least one, if not more immune cells
Suppresses cytokine modulated immune system
Antagonizes TLR-mediated production of NF-kB – reducing inflammation, potentially down-regulating oncogenes